In a very interesting period for Bayer in the way of "pharmacists" was Hoffenheim. Last round was a long-awaited event for the foes of the Leverkusen club, which lost in the German championship for the first time since the season before last. Moreover, the defeat became for Bayer as painful as possible, as it happened in their home walls. Even after the national champion beat Leipzig 2-0 in the 45th minute. Now Bayer has to rehabilitate for the defeat away against not the easiest opponent. Hoffenheim at the end of last season took seventh place, which gave them the right to participate in the Europa League. "Village" all their way in the Bundesliga had the status of a "home" team, where the opponents are set up in a special way. Bookmakers have identified the guests as favourites for the upcoming meeting, offering odds of 1.50 on their victory.

Hoffenheim played their first match of the season against Holstein Kille at home and "welcomed" the newcomer to the division with three goals, to which the opponent managed to respond only twice. As confidently "villagers" won in the first meeting, so convincingly lost in the second, where their opponent in Frankfurt am Main was the local Eintracht (1-3).

The first matches of the new season were difficult for Bayer. In the German Super Cup, the team was already in the minority in the 37th minute, lost in the course of the meeting and had to save themselves in the 88th minute. Already in the penalty shootout "pharmacists" were stronger than Stuttgart. The first round of the Bundesliga was also difficult. Bayer played in Mönchengladbach and allowed Borussia to score two goals during the meeting. Wirz struck the winning blow on 90+11 minutes after his own unrealised penalty - 3:2. The defeat to Leipzig was dramatic, but deserved, as you can't relax against such opponents, even if you have a two-goal advantage. Since 2015, Bayer has never beaten Hoffenheim without conceding once. At the same time, the "villagers" had a lot of such victories over the "pharmacists" during this period. Bayer historically plays hard with Hoffenheim, so do not count on an easy away win.